Ambrisentan (Volibris)



5 mg /day ou 10 mg /day


  • Hypersensitivity to ambrisentan or any of the excipients.
  • Pregnancy.
  • Severe hepatic impairment (with or without cirrhosis).
  • Initial values of liver transaminases (aspartate aminotransferase [AST] and / or alanine aminotransferase [ALT]) exceeding 3 times the upper limit of normal (> 3 × ULN).
  • Idiopathic pulmonary fibrosis with or without secondary pulmonary hypertension.