Ambrisentan (Volibris)

(Volibris)

Dosage

5 mg /day ou 10 mg /day

Contra-indications

  • Hypersensitivity to ambrisentan or any of the excipients.
  • Pregnancy.
  • Severe hepatic impairment (with or without cirrhosis).
  • Initial values of liver transaminases (aspartate aminotransferase [AST] and / or alanine aminotransferase [ALT]) exceeding 3 times the upper limit of normal (> 3 × ULN).
  • Idiopathic pulmonary fibrosis with or without secondary pulmonary hypertension.

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