Atrial fibrillation (AF)

Diagnostic and therapeutic approach

  1. Diagnosis
  2. Treatment
  3. Scores
  4. Pharmaceuticals
  5. ESC recommandations

Pharmaceuticals

  1. Amiodarone
  2. Oral anticoagulants
  3. ß-Blockers
  4. Dabigatran (Pradaxa)
  5. Digitalis (Digoxine)
  6. Diltiazem (Dilzem)
  7. Dronedarone (Multaq)
  8. Flecainide (Tambocor)
  9. Ibutilide (Corvert)
  10. Propafenone (Rytmonorm)
  11. Rivaroxaban (Xarelto)
  12. Sotalol (Sotalex)
  13. Verapamil (Isoptin)
  14. Vernakalant (Brinavess)
  15. Apixaban (Eliquis)
  16. Edoxaban (Lixiana)

Verapamil (Isoptin)

(Isoptin)

Bolus

5-10 mg ou 0.075-0.15 mg/kg i.v. in 2 min, if needed repeat after 30 min, then 0.1-0.5 mg/kg/min i.v.c.

Maintenance

120-480 mg/day p.o.

## Contra-indications

  • Hypersensitivity to the active substance or to any of the excipients.
  • Cardiogenic shock.
  • Severe conduction abnormalities (2nd or 3rd degree AV block), sick sinus syndrome (bradycardia-tachycardia syndrome).
  • Heart failure with reduced ejection fraction less than 35%.
  • AF / atrial flutter in patients with an accessory pathway (eg Wolff-Parkinson-White, Lown-Ganong-Levine.).

[(http://www.drugs.com/verapamil.html) ]