Atrial fibrillation (AF)

Diagnostic and therapeutic approach

  1. Diagnosis
  2. Treatment
  3. Scores
  4. Pharmaceuticals
  5. ESC recommandations

Pharmaceuticals

  1. Amiodarone
  2. Oral anticoagulants
  3. ß-Blockers
  4. Dabigatran (Pradaxa)
  5. Digitalis (Digoxine)
  6. Diltiazem (Dilzem)
  7. Dronedarone (Multaq)
  8. Flecainide (Tambocor)
  9. Ibutilide (Corvert)
  10. Propafenone (Rytmonorm)
  11. Rivaroxaban (Xarelto)
  12. Sotalol (Sotalex)
  13. Verapamil (Isoptin)
  14. Vernakalant (Brinavess)
  15. Apixaban (Eliquis)
  16. Edoxaban (Lixiana)

Digitalis (Digoxine)

(Digoxine)

Bolus

0.5 à 1 mg i.v. in 10 minutes.

Maintenance

0.125 à 0.5 mg/day.

Contra-indications

  • Renal failure.
  • Conduction disorders and WPW.
  • Hypokalemia.
  • Unsubstituted Hypothyroidism. If ventricular tachyarrhythmias and / or nausea and vomiting, think of digitalis toxicity.

In this case and in the presence of hemodynamic instability or severe hyperkalemia, consider Fab (digoxin-binding antibody fragments).

Caution in patients with renal failure!

http://www.drugs.com/ingredient/digoxin.html