Pulmonary embolism (PE)

Diagnostic and therapeutic approach

Edoxaban (Lixiana)



60 mg/j or 30 mg/day if renal failure or weight < 60 kg.

Absolute contra-indications

  • Hypersensitivity to active principle or excipients.
  • Acute bleeding.
  • Severe liver disease or high risk of bleeding.
  • Lesions or sickness at high risk of bleeding.
  • Pregnancy.

Pay attention to drugs interaction and inhibitors of CYP3A4 and/or P-gp.